Does Depression Make You Tired?

does depression make you tired? therapy in wilkes-barre pa with Dr. John G Kuna and Associates

Depression is a common mental health condition that affects millions of people worldwide. While the primary symptoms of depression are often associated with changes in mood and behavior, it can also lead to physical symptoms such as fatigue and exhaustion. This blog will explore the relationship between depression and fatigue and how it affects individuals.


Depression and Fatigue

Fatigue is a feeling of tiredness that can affect both the mind and body. It is a common symptom of depression, and many people who suffer from depression often experience chronic fatigue. Many factors, including physical activity, lack of sleep, and stress, can cause fatigue. However, when fatigue is related to depression, it is often more persistent and unrelenting.

The exact reason why depression causes fatigue is not fully understood. However, research suggests that depression may affect the levels of certain chemicals in the brain, such as serotonin and norepinephrine, which regulate sleep, mood, and energy levels. Additionally, depression can lead to changes in behavior, such as reduced physical activity and poor nutrition, contributing to fatigue.


Effects of Fatigue on Depression

Fatigue can have a significant impact on depression in several ways.

First, fatigue can worsen other symptoms of depression, such as low mood, lack of motivation, and feelings of hopelessness. This can create a vicious cycle, where fatigue and depression reinforce each other, making it harder to break out of the negative cycle.

Second, fatigue can make it difficult for individuals to engage in activities they enjoy or to participate in social relationships. This can lead to social isolation and a lack of support, further exacerbating depression.

Third, fatigue can also affect cognitive functioning, making concentrating, remembering information, and making decisions harder. This can make it harder for individuals to perform at work or school, leading to further stress and anxiety.

Finally, chronic fatigue can lead to feelings of frustration, guilt, and helplessness. Individuals may feel frustrated that they cannot do what they want, guilty that they are not living up to their responsibilities, and helpless to change their situation. These feelings can further contribute to low mood and depression.

does depression make you tired?

Treatment for Fatigue and Depression

The treatment for fatigue and depression typically involves a combination of medication, therapy, and lifestyle changes.


Antidepressants are often prescribed to help regulate the levels of chemicals in the brain that affect mood and energy levels. Stimulants may also be prescribed to help with fatigue, although they are typically not used as a first-line treatment for depression.


Psychotherapy, or talk therapy, can be helpful in identifying and addressing the underlying causes of depression, such as negative thought patterns, trauma, or stress. Cognitive-behavioral therapy (CBT) is a type of therapy that focuses on identifying and changing negative thought patterns and behaviors that contribute to depression.

Lifestyle Changes

Making lifestyle changes can also help manage fatigue and depression. Regular exercise, for example, has been shown to improve energy levels and reduce symptoms of depression. A healthy diet and good sleep hygiene can also help regulate energy levels and improve overall well-being. Additionally, stress management techniques such as mindfulness meditation, deep breathing exercises, or yoga can help reduce stress and improve mood.

It is important to note that treatment for fatigue and depression is individualized, and what works for one person may not work for another. Finding the right treatment plan for you may take some trial and error. A mental health professional can provide guidance and support in finding the right treatment plan for your needs.



Depression and fatigue are closely related, and individuals who suffer from depression often experience persistent fatigue. Fatigue can significantly impact a person’s mental health and well-being, worsening symptoms of depression and leading to feelings of hopelessness and guilt. However, with proper treatment, including medication, therapy, and lifestyle changes, individuals can manage their symptoms and improve their overall quality of life. It is essential to seek professional help if you are experiencing persistent fatigue or symptoms of depression.

Dr. John G Kuna and Associates offer therapy in Wilkes-Barre, Pennsylvania. With 14 other convenient locations across Eastern PA, we’re ready to meet your needs where you’re at. We offer both in-person and telehealth therapy appointments. Contact us today to schedule your appointment!

Brooke Lamberti

Brooke Lamberti is a content writer based out of Scranton, Pennsylvania. She received a Bachelor of Science in Psychology from Marywood University, and has prior career experience working in social work and domestic violence advocacy. She has a passion for writing and helping others.